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Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-59638

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Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-59638 Descriptor: Activin receptor type-1, N-(4-methoxyphenyl)-4-[3-(pyridin-3-yl)-1H-pyrazol-4-yl]pyrimidin-2-amine, SULFATE ION Authors: Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. Deposit date: 2018-07-27 Release date: 2019-03-20 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.01 Å) Cite: Bis-Heteroaryl Pyrazoles: Identification of Orally Bioavailable Inhibitors of Activin Receptor-Like Kinase-2 (R206H). Chem. Pharm. Bull., 67, 2019
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2018-07-27
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