We developed Cas9 fusion proteins containing single-stranded DNA-binding proteins and a 20-amino acid motif with single-stranded DNA-binding function. These fusion proteins demonstrated higher efficie

NIAID Data Ecosystem40

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藻类生物学

医学成像

Single computed slice from a tomographic volume of a blue green algae grown under low light conditions.

DataCite Commons2020-08-27 更新30

Iron metabolism in Ostreococcus tauri. Ostreococcus tauri strain:OTH95

藻类生物学

转录组响应

We investigated short-term and long-term transcriptional responses to iron limitation in the picoeukaryotic alga Ostreococcus tauri by combining physiological responses and RNA sequencing.

NIAID Data Ecosystem50

Application of iGUIDE to identify potential off-target cleavage caused by Cas9/PD1 sgRNA

CRISPR-Cas9基因编辑

CAR-T细胞疗法

We successfully develop a two-in-one approach to generate non-viral genome specific targeted CAR T cells through CRISPRCas9. In the adoptive therapy for relapsedrefractory aggressive B-cell non-Hodgki

NIAID Data Ecosystem40

Genetic variance of C. reinhardtii according to Cas9-mediated NHEJ

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