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ACRIDINE BINDING TO DNA

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Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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ACRIDINE BINDING TO DNA Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 9-AMINO-(N-(2-DIMETHYLAMINO)ETHYL)ACRIDINE-4-CARBOXAMIDE, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3') Authors: Thorpe, J.H, Todd, A.K, Cardin, C.J. Deposit date: 1999-02-18 Release date: 2003-03-04 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethlyamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5Br-U)ACG)2 at 1.3-angstrom resolution J.Med.Chem., 42, 1999

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1999-02-18
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