Genetic structure and demographic history of house mice in Western Europe inferred using whole genome sequences

The movement of human populations has greatly influenced the distributions of human commensals. Patterns of genetic variation in contemporary populations can shed light on their demographic history, including long-range migration events and changes in effective population size. The western house mouse, Mus musculus domesticus, is a human commensal and an outstanding model organism for studying a wide variety of traits and diseases. However, we have few genomic resources for wild mice and only a rudimentary understanding of the demographic history of house mice in Europe. Here, we sequenced 59 whole-genomes of mice collected from England, Scotland, Wales, Guernsey, northern France, Italy, Portugal, and Spain. We combined this dataset with 24 previously published sequences from southern France, Germany, and Iran, and compared patterns of population structure and inferred demographic parameters for house mice in Western Europe to patterns seen in humans. Principal component and phylogeneti..., , , # Data from: **Genetic structure and demographic history of house mice in Western Europe inferred using whole genome sequences**

 https://doi.org/10.5061/dryad.s1rn8pkgh

* **ALL_Europe_unfiltered_merged_noAlloption.vcf.gz**

Unfiltered vcf of 59 wild-caught house mice from England, Scotland, Wales, Guernsey, northern France, Italy, Portugal, and Spain collected and deposited as prepared specimens in the University of Michigan, Museum of Zoology, and 24 wild-caught mice from southern France, Germany, and Iran from a previous publication (Harr et al. 2016). Sequences were aligned to the mouse reference genome (GRCm38/mm10, RefSeq: GCF_000001635.20). See Tables S1 and S2 of the associated manuscript for sample information, including sample locations and alignment statistics.

**Sharing/Access information**

The raw fastq files used to generate this data is accessible from:

* NCBI SRA BioProject ID PRJNA1050608

- **ALL_Europe_83samples_filtered_merged_autosomes.recode.vcf.gz**

Filtered...,