Crystal structure of human beta-secretase in complex with NVP-BAV544
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Crystal structure of human beta-secretase in complex with NVP-BAV544 Descriptor: (3S,14R,16S)-16-[(1R)-1-hydroxy-2-{[3-(1-methylethyl)benzyl]amino}ethyl]-3,4,14-trimethyl-1,4-diazacyclohexadecane-2,5- dione, Beta-secretase 1 Authors: Rondeau, J.-M. Deposit date: 2008-07-18 Release date: 2009-02-24 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorg.Med.Chem.Lett., 19, 2009
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2008-07-18
