Mesoscale DNA Feature in Antibody-Coding Sequence Facilitates Somatic Hypermutation
收藏NIAID Data Ecosystem2026-03-14 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA918596
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资源简介：
Somatic hypermutation (SHM), initiated by activation-induced cytidine deaminase(AlD), generates a pool of mutations in antibody-coding sequence to allow affinitymaturation upon pathogen invasion. Why these mutations are intrinsically focusedon the three nonconsecutive complementarity-determining-regions (CDRs) remainsenigmatic.
创建时间：
2023-01-05
