Structure of HIV-1 Protease in Complex with Inhibitor KNI-1657

Structure of HIV-1 Protease in Complex with Inhibitor KNI-1657 Descriptor: (4R)-N-[(2,6-dimethylphenyl)methyl]-3-[(2S,3S)-3-[[(2S)-2-[(7-methoxy-1-benzofuran-2-yl)carbonylamino]-2-[(3R)-oxolan-3 -yl]ethanoyl]amino]-2-oxidanyl-4-phenyl-butanoyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, GLYCEROL, HIV-1 PROTEASE Authors: Adachi, M, Hidaka, K, Kuroki, R, Kiso, Y. Deposit date: 2017-10-29 Release date: 2018-07-18 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (0.85 Å) Cite: Identification of Highly Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomimetics with P2 Tetrahydrofuranylglycine. J. Med. Chem., 61, 2018