Crystal Structure of Human MMP-13 complexed with a phenyl-2H-tetrazole compound
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Crystal Structure of Human MMP-13 complexed with a phenyl-2H-tetrazole compound Descriptor: 4-{[({3-[2-(4-methoxybenzyl)-2H-tetrazol-5-yl]phenyl}carbonyl)amino]methyl}benzoic acid, ACETOHYDROXAMIC ACID, CALCIUM ION, ... Authors: Shieh, H.-S, Pavlovsky, A.G, Collins, B, Schnute, M.E. Deposit date: 2009-10-25 Release date: 2010-11-10 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg.Med.Chem.Lett., 20, 2010
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2009-10-25
