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Microarray analysis of WT and Drd2-/- striatal tissue from C57BL/6 mice

Alliance of Genome Resources2026-08-01 收录

纹状体转录组

Drd2基因敲除研究

数据链接：

http://www.informatics.jax.org/gxd/htexp_index/summary?arrayExpressID=E-GEOD-41638 数据链接链接失效反馈

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资源简介：

Drd2 regulates striatal gene networks. WT and KO striatal tissue were dissected from 2-month-old naive male C57BL/6 genetic background mice and subjected to microarray analysis.

应用场景：

神经毒性

纹状体转录组

Rats were exposed to manganese (Mn) at 25mg/kg for 15 days. After the exposure, the RNA was collected from the striatum tissue (specific part the brain) of the control group (untreated) and Mn-exposed

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High motivation for exercise is associated with altered chromatin regulators of monoamine receptor gene expression in the striatum of selectively bred mice. Mus musculus domesticus

运动神经机制

纹状体转录组

Though exercise is critical for health and wellbeing, many lack the motivation to exercise, and it is unclear how motivation might be increased. To uncover the molecular underpinnings of increased mot

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Transcriptional profiling of striatum in METH self-administered rats [mRNA]

甲基苯丙胺成瘾

纹状体转录组

This study aimed to identify changes in novel miRNAs and their target genes during METH self-administration and investigate their roles in METH-induced locomotion. RNA sequencing analysis revealed tha

Alliance of Genome Resources00

Diurnal alterations in gene expression across striatal subregions in psychosis

精神病基因节律

纹状体转录组

Background: Psychosis is a defining feature of schizophrenia and highly prevalent in bipolar disorder. Notably, individuals suffering with these illnesses also have major disruptions in sleep and circ

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Long-access cocaine intravenous self-administration; transcriptional profiling of medium spiny neurons in the dorsal striatum of Drd2-TRAP (CP101) mice

可卡因自我给药

纹状体转录组

TRAP translational profiling is a method that allows investigators to genetically characterize specific cell types in complex tissues such as mouse brain. Using this technique we obtained RNA-Seq dat

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Microarray analysis of WT and Drd2-/- striatal tissue from C57BL/6 mice

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