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PUVA pretreatment leads to significant reduction in imiquimod induced psoriatic phenotype with gene expression signature associated with senescence

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE100774
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PUVA pretreatment leads to develop early senescence confirmed by p16, p21 and SA-β-GAL positivity which was completely normalised by longer gap. Indicating that PUVA pretreatment causes conditioning set of genes that led to a marked delay in psoriasis development. To study the induction and phenotypes development of Aldara-mediated dermatitis in mice pretreated with PUVA in comparison to UVB
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2021-07-25
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