five

Crystal structure of human PDE1B with inhibitor 3

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Protein Data Bank Japan2023-11-08 更新2026-03-21 收录
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Crystal structure of human PDE1B with inhibitor 3 Descriptor: (11R,15S)-4-{[4-(6-fluoropyridin-2-yl)phenyl]methyl}-8-methyl-5-(phenylamino)-1,3,4,8,10-pentaazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, GLYCEROL, ... Authors: Ida, K, Lane, W, Snell, G, Sogabe, S. Deposit date: 2016-01-07 Release date: 2016-02-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases J.Med.Chem., 59, 2016
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2016-01-07
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