首页/数据集/Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes

Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes

NIAID Data Ecosystem2026-03-10 收录

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中心体信号通路

数据链接：

https://www.omicsdi.org/dataset/bioimages/S-JCBD-201410001 数据链接链接失效反馈

官方服务：

资源简介：

Cells were fixed and immunostained with α-Plk1 (red), α-tubulin (green), and DNA (blue).

应用场景：

创建时间：

2018-11-29

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纺锤体检查点

3HA-Bfa1 (red) localization in wild-type metaphase cells. Tubulin (green) and DAPI (blue) are also shown.

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Sgo1 Regulates Both Condensin and Ipl1/Aurora B to Promote Chromosome Biorientation

染色体双极化机制

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Correct chromosome segregation is essential in order to prevent aneuploidy. To segregate sister chromatids equally to daughter cells, the sisters must attach to microtubules emanating from opposite sp

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Cdc14 Early Anaphase Release, FEAR, Is Limited to the Nucleus and Dispensable for Efficient Mitotic Exit

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细胞周期检查点

Cdc14 phosphatase is a key regulator of exit from mitosis, acting primarily through antagonism of cyclin-dependent kinase, and is also thought to be important for meiosis. Cdc14 is released from its s

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Rock inhibitors target SRSF2 leukemia by disrupting cell mitosis and nuclear morphology

白血病靶向治疗

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Spliceosome machinery mutations are common early mutations in myeloid malignancies, however effective targeted therapies against them are still lacking. In the current study, we used an in vitro high-

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Additional file 4 of NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis

胃癌发生机制

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Supplementary Material 4.

Figshare2025-01-21 更新40