Tricyclic series of Hsp90 inhibitors

Tricyclic series of Hsp90 inhibitors Descriptor: 1-(3H-imidazo[4,5-c]pyridin-2-yl)-3,4-dihydropyrido[2,1-a]isoindol-6(2H)-one, 4-(5-METHYL-4-PHENYLISOXAZOL-3-YL)BENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP 90-ALPHA Authors: Dupuy, A, Vallee, F. Deposit date: 2011-05-25 Release date: 2011-10-19 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Tricyclic Series of Heat Shock Protein 90 (Hsp90) Inhibitors Part I: Discovery of Tricyclic Imidazo[4,5-C]Pyridines as Potent Inhibitors of the Hsp90 Molecular Chaperone. J.Med.Chem., 54, 2011