Kinase domain of cSrc in complex with inhibitor RL45 (Type II)
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Kinase domain of cSrc in complex with inhibitor RL45 (Type II) Descriptor: 1-{4-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]urea, Proto-oncogene tyrosine-protein kinase Src Authors: Grutter, C, Kluter, S, Getlik, M, Rauh, D. Deposit date: 2008-10-31 Release date: 2009-06-02 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc J.Med.Chem., 52, 2009
创建时间：
2008-10-31
