Comparison of gene expression alterations induced by distinct PI3K inhibitors
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE33643
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The goal is the characterization of the off-target activity of BKM120 observed in A2058 human melanoma cell line at IC90 concentration (3.606 µM) but not at lower concentrations. Controls are BEZ235, GDC0941, showing no off-target activity. A secondary objective is the characterizations of drug effects on transcript expression with respect to a control treatment (DMSO) of those PI3K inhibitors. 3 compounds, 3 concentrations per compound treatment, DMSO control treatement, 4 biological replicates
创建时间：
2019-03-25
