Two photon calcium imaging recordings of spontaneous activity from mouse somatosensory cortex in wild-type and Fmr1 knock-out mice from three developmental age groups.

This dataset contains in vivo two photon Ca2+ imaging recordings obtained from
Layer 2/3 somatosensory cortex of several mice of two genotypes (wild-type C57/B6
and Fmr1 knock-out) and three developmental age groups (postnatal days 9—11, 14—16,
and 30—40). The mice were un-anesthetized, head-fixed, and not engaged in any
experimental task. The dataset comprises: 1) the raw TIFF imaging movies, 2) estimated
firing rates of individual neurons (MATLAB), and 3) the estimated anatomical distance
between each pair of recorded cells (MATLAB). The number of animals in each group
ranges from 6—13, while the number of simultaneously imaged neurons in each animal
ranges from 40—149. Each recording was performed at a frame rate of 3.9 Hz, and the
total duration of each recording is approximately 7—8 minutes.