Additional file 1 of Identifying primary and secondary MLH1 epimutation carriers displaying low-level constitutional MLH1 methylation using droplet digital PCR and genome-wide DNA methylation profiling of colorectal cancers

Additional file 1. Table S1: Sequences of primers included in this study. Table S2: The characteristics of 38 CRCs from six reference CRC groups. Table S3: The characteristics of 44 tumour and 14 normal colonic mucosal samples from the 43 people included in the study. Table S4: Summary of somatic mutations occurrent in key CRC genes and CRC subgroups associated with frequent or less frequent somatic mutation in the described gene. Table S5: Differentially Methylated Regions between tumours of MLH1 epimutation carriers and sporadic MLH1 methylated CRCs. Table S6: MLH1 promoter methylation levels in non-tumour DNA samples measured by methylation-sensitive digital droplet PCR.