Dataset SARS-CoV2-cytokines y2021m02 [50]

Comparison of
cytokines levels among COVID-19 patients living at sea level and high altitude

ABSTRACT

Objective: The objective of
this study was to compare the levels of pro-inflammatory cytokines (IL-6, IL-2,
IL-10, INF-α and IFN-γ) in COVID-19
patients and healthy subjects, residing in two cities of Peru at different
altitudes.

Results: A total of 35 COVID-19 patients and 10 healthy subjects were
recruited from each study site. The mean levels of IL-6 (p<0.03)
and TNF-α (p<0.01) were significantly
different among the study groups. In the case of IL-6, patients from Lima had a
mean level of 16.2 pg/ml (healthy) and 48.3 pg/ml (COVID-19), meanwhile,
patients from Huaraz had levels of 67.3 pg/ml (healthy) and 97.9 pg/ml
(COVID-19). Regarding TNF-α, patients from Lima had a mean
level of 25.9 pg/ml (healthy) and 61.6 pg/ml (COVID-19), meanwhile, patients from
Huaraz had levels of 89.0 pg/ml (healthy) and 120.6 pg/ml (COVID-19). The
levels of IL-2, IL-10 and IFN-γ) were not significantly different in the study
groups.