25 most upregulated mRNAs in alveolar macrophages of smokers.

aChange indicates smoker-to-nonsmoker expression ratio in alveolar macrophages from this study.bExpression change of indicated mRNA described by Woodruff et al [25] in analysis of alveolar macrophage smokers and nonsmokers (GEO dataset 1269).cExpression change of indicated mRNA described by Martinez et al [55] in analysis of monocyte-derived macrophages (MDMs) polarized toward M1 or M2a phenotypes relative to unstimulated MDMs (GEO datasets 2429 and 2430).(“up” indicates upregulation; “down” indicates downregulation; “no change” indicates no change and “ND” indicates not determined).