Discovery of diagnostic biomarker and molecular mechanisms of placenta accreta spectrum

Transcriptome analysis of FFPE placenta of placenta accreta spectrum, over increta. Pre-diagnosis is essential to safely deal with placenta accrete spectrum, but definitive diagnostic markers have not yet been established. We conducted a transcriptome analysis of FFPE placenta to establish early diagnostic markers for placenta accreta. We analyzed 11 FFPE placenta (3 control, 2 increta and 6 percreta) using the GeneChipTM Human Gene 2.0 ST Arrays. Array data was processed by Transcriptome Analysis Console 4.0 software package . No techinical replicates were performed.