Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor

Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor Descriptor: 5-(2-amino-[1,2,4]triazolo[1,5-c]quinazolin-5-ylmethyl)-benzene-1,3-diol, HEAT SHOCK PROTEIN HSP 90-ALPHA Authors: Casale, E, Amboldi, N, Brasca, G, Caronni, D, Colombo, N, Dalvit, C, Felder, E.R, Fogliatto, G, Isacchi, A, Mantegani, S, Polucci, P, Riceputi, L, Sola, F, Visco, C, Zuccotto, F, Casuscelli, F. Deposit date: 2014-04-03 Release date: 2014-07-09 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Fragment-Based Hit Discovery and Structure-Based Optimization of Aminotriazoloquinazolines as Novel Hsp90 Inhibitors. Bioorg.Med.Chem., 22, 2014