The X-ray co-crystal structure of human CDK6 and Abemaciclib.
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The X-ray co-crystal structure of human CDK6 and Abemaciclib. Descriptor: Cyclin-dependent kinase 6, N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine Authors: Chen, P, Ferre, R.A, Deihl, W, Yu, X, He, Y.-A. Deposit date: 2016-08-02 Release date: 2016-08-24 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance. Mol.Cancer Ther., 15, 2016
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2016-08-02
