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An estimate of fitness reduction from mutation accumulation in a mammal allows assessment of the consequences of relaxed selection: Dataset

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Zenodo2024-07-19 更新2026-05-26 收录
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Supplementary files (data and analysis) for "An estimate of fitness reduction from mutation accumulation in a mammal allows assessment of the consequences of relaxed selection" Supplementary File 1: C3H_pheno_fix_Jun7_2023_nolowmut.csv Data for all mice in MA experiment including: mouse ID, sire, dam, generation, mating ID, sex, weight at 3 weeks, weight at 6 weeks, tail length, litter size, litter ID, line ID Supplementary File 2: C3H_pheno_Kontrol_June2023.csv Data for all control mice including: mouse ID, sire, dam, generation, mating ID, sex, weight at 3 weeks, weight at 6 weeks, tail length, litter size, litter ID, line ID Supplementary File 3: C3H_birthdates.csv Data for all C3H mice including: mouse ID, birthdate Supplementary File 4: MA_pheno.R R code for visualising trait data, running linear regressions, and comparing control and MA experiment data Supplementary File 5: C3H_pheno_burnin20_Jun7_2023_nolowmut.csv Data for all mice in MA experiment including a 20 generation burn-in to simulate mutation-drift balance for Animal model analyses: mouse ID, sire, dam, generation, mating ID, sex, weight at 3 weeks, weight at 6 weeks, tail length, litter size, litter ID, line ID Supplementary File 6: asreml_C3H_ALL.R R code for estimating mutational heritabilities using mixed model analysis Supplementary File 7: C3H_ped_rekey_Jun2023.csv Pedigree data for all mice in MA experiment Supplementary File 8: C3H_ped_rekey_KEY.csv Key for pedigree data file Supplementary File 9: plot_pedigree_tree_MS_final.R R code for visualising pedigree of mice in MA experiment

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2024-07-19
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