Data from: Host population bottlenecks drive parasite extinction during antagonistic coevolution

Host-parasite interactions are often characterized by large fluctuations
in host population size, and we investigated how such host bottlenecks
affected coevolution between a bacterium and a virus. Previous theory
suggests that host bottlenecks should provide parasites with an
evolutionary advantage, but instead we found that phages were rapidly
driven to extinction when coevolving with hosts exposed to large genetic
bottlenecks. This was caused by the stochastic loss of sensitive bacteria,
which are required for phage persistence and infectivity evolution. Our
findings emphasize the importance of feedbacks between ecological and
coevolutionary dynamics, and how this feedback can qualitatively alter
coevolutionary dynamics.