Uracil Nucleosides with Reactive Group at C5 Position: 5‑(1-Halo-2-sulfonylvinyl)uridine Analogues
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资源简介：
The transition-metal-catalyzed or radical-mediated halosulfonylation of 5-ethynyluridine provided (E)-(1-halo-2-tosylvinyl)uridines. These (β-halo)vinyl sulfones undergo efficient stereoselective addition–elimination with amines or thiols to provide Z-β-aminovinyl or E-β-thiovinyl sulfones tethered to the C5 position of the uracil ring.
创建时间：
2016-03-14
