Global changes of transcriptomes between 3-month-old and 1-year-old human right atria
收藏中国科技资源共享网2026-05-07 更新2026-02-07 收录
下载链接：
https://escience.org.cn/metadata/detail?cstrId=CSTR:17970.11.A001G.202009.372.V1.0&id=774e74221ac511e980780242ac120006:CSTR:A0006.11.A001G.202009.372.V1.0
下载链接
链接失效反馈官方服务：
资源简介：
Previous study showed that there are more cell cycle active cardiomyocytes (CMs) in 3-month-old (3M) than1-year-old (1Y) human atria, and extracellular matrix (ECM) from mouse atria benefits neonatal CMs proliferation. We investigate the global changes of transcriptomes between 3M and 1Y human atria and whether ECM from 3M human atria improves myocardium infarct recovery. RNAseq results showed that the major changes between 3M and 1Y human atria were ECM. 3M –ECM increased CM cell cycle activities and rescue mouse heart from injury. We conclude that 3M-ECM hold a therapeutic effect on myocardium infarction.
提供机构：
国家人口健康科学数据中心
创建时间：
2020-11-24
