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Human LRH-1 bound to the agonist 2N and a fragment of the Tif2 coregulator

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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Human LRH-1 bound to the agonist 2N and a fragment of the Tif2 coregulator Descriptor: N-[(1S,3aR,6aR)-5-hexyl-4-phenyl-3a-(1-phenylethenyl)-1,2,3,3a,6,6a-hexahydropentalen-1-yl]acetamide, Nuclear receptor coactivator 2, Nuclear receptor subfamily 5 group A member 2 Authors: Mays, S.G, Ortlund, E.A. Deposit date: 2019-04-29 Release date: 2019-08-28 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.174 Å) Cite: Development of the First Low Nanomolar Liver Receptor Homolog-1 Agonist through Structure-guided Design. J.Med.Chem., 62, 2019

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2019-04-29
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