Ptp4a3 (commonly known as PRL-3) is an enigmatic member of the Ptp4a family of prenylated protein tyrosine phosphatases that are highly expressed in many human cancers. Despite strong correlations wit
Urinary albumin to creatinine ratios from BAMBI+/+ and BAMBI−/− mice at baseline and two weeks after unilateral nephrectomy. BUN levels from BAMBI+/+ and BAMBI−/− mice at baseline and 2 weeks after un
Bid is a Bcl-2 family protein. In addition to its pro-apoptosis function, Bid can also promote cell proliferation, maintain S phase checkpoint, and facilitate inflammasome activation. Bid plays import
No significant differences in heart weight, body weight, HW:BW ratio, or age were found between FL and KO hearts at 1 and 4 weeks post-tamoxifen injection. Unpaired two-tailed t tests were used to com
本数据集为结肠隐窝失巢凋亡的基于代理模型(ABM)模拟数据,聚焦结直肠癌(CRC)发生机制研究。模型包含隐窝口腔几何结构精准表征等新特性,模拟再现了细胞死亡局限于隐窝口腔小区域等与体内观察一致的涌现行为,支持探究隐窝细胞数量调控机制及细胞形状假设对生物学行为的影响。 论文“An agent-based model of anoikis in the colon crypt displays nov