Distribution of covariates at initiation of the individualized MDR-TB regimen.

*Patients enrolled prior to March 1, 2001 were more likely to have received the standard Category II retreatment regimen after failure of Category I than patients enrolled after this date, when national policy changed. ‡<18.5 in women, <20 in men; or malnutrition established clinically. €≤30% in women, ≤36% in men; when missing, also used hemoglobin ≤10 in women and ≤12 in men. ¥Dyspnea; resting heart rate >26/minute. £Isolate resistant to at least isoniazid, rifampin, fluoroquinolone, and injectable (kanamycin, capreomycin or amikacin). §This includes the following comorbidities: cardiovascular disease (12), diabetes (15), hepatitis or cirrhosis (7), epilepsy/seizures (10), renal insufficiency (6), psychiatric disorder (101), ever smoked (59), ever used/abused alcohol or other substance (49). Distribution of covariates at initiation of the individualized MDR-TB regimen.