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PIKFYVE Inhibition Mitigates Disease in Models of Diverse Forms of ALS [1]

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NIAID Data Ecosystem2026-05-01 收录
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RNA sequencing analysis of human iPSC-derived motor neurons generated from one C9ORF72 ALS/FTD patient line, treated with DMSO or Apilimod. The goal of this study is to evaluate the effect of PIKFYVE inhibitor in rescuing ALS motor neuron degeneration. Overall design: Gene expression profiling analysis of RNA-seq data for the effect of PIKFYVE inhibitor, Apilimod, on C9ORF72 ALS/FTD iPSC-derived motor neurons.

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2023-10-18
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