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Microwave-Assisted Cascade Strategy for the Synthesis of Indolo[2,3‑b]quinolines from 2‑(Phenylethynyl)anilines and Aryl Isothiocynates

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Figshare2017-02-09 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Microwave-Assisted_Cascade_Strategy_for_the_Synthesis_of_Indolo_2_3_i_b_i_quinolines_from_2_Phenylethynyl_anilines_and_Aryl_Isothiocynates/4635763
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The in situ generated o-alkynylthioureas obtain by reacting 2-(phenylethynyl)­anilines and aryl isothiocynates undergo efficient cascade cyclization in the presence of Ag2CO3 to form indoloquinolines under microwave heating. The present tandem process allows the generation of a variety of indolo­[2,3-b]­quinolines derivatives in good to moderate yields with a wide functional group tolerance.
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2017-02-09
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