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Robustness of the no-interference model for ordering genetic markers.

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PubMed Central1992-04-01 更新2026-05-16 收录
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Under the assumption of no chromatid interference, we derive constraints on the probabilities of the different recombination patterns among m + 1 genetic loci. An application of these constraints is a proof that the ordering of the loci that maximizes the likelihood under the assumption of no interference is, in fact, a consistent estimator of the true order even when there is interference. IMAGES:

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1992-04-01
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