The number of SARE containing genes is significantly enriched on genes up-regulated upon bicuculline triggering of neuronal activity.

Comparative analysis of the list of SARE containing genes with three independent studies reporting mRNA changes in gene expression in the accessory olfactory bulb [21]; cortical cells [22]; and hippocampal neuronal cultures [23]. The table shows the lists of the SARE genes that were found to be up-regulated (upper part), or down-modulated (lower part) in each study. P-values for random coincidence are shown. Not significance coincidence was observed when compared to genes that are down-regulated.