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HIV-1 protease with mutation L76V in complex with GRL-5010 (gem-difluoro-bis-tetrahydrofuran as P2 ligand)

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6dj7
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HIV-1 protease with mutation L76V in complex with GRL-5010 (gem-difluoro-bis-tetrahydrofuran as P2 ligand) Descriptor: (3R,3aS,6aS)-4,4-difluorohexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ... Authors: Wong-Sam, A.E, Wang, Y.F, Weber, I.T. Deposit date: 2018-05-24 Release date: 2018-10-17 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.31 Å) Cite: Drug Resistance Mutation L76V Alters Nonpolar Interactions at the Flap-Core Interface of HIV-1 Protease. ACS Omega, 3, 2018
创建时间:
2018-05-24
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