High-throughput sequencing reveals induction of drug metabolism in various cholestatic livers
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
下载链接：
http://data.iscr.ac.cn/Article?id=7a8145988f38ab5dd837b12ba8f06b04
下载链接
链接失效反馈官方服务：
资源简介：
Cholestasis is a multifactorial disorder that compromises liver function. We wanted to examine Phase I and II drug metabolism in cholestatic livers. We performed high-throughput sequencing on livers from Fxr-/- Shp-/- double knockout mice, which mimic juvenile cholestasis. Next, we used comparative transcriptomic approach to test if the induction in drug metabolism is also seen in models of liver injury, including steatosis, regeneration and bile acid-stressed livers.
提供机构：
UIUC
创建时间：
2022-02-20
