Analysis of simulated disease architecture with 180 causal 1Mbp loci yielding a true . In each locus, 1–10 causal variants were sampled from either low-frequency () of common (MAF) WTCCC2 SNPs. For ea
Our goal is to develop a general strategy to decompose a random variable X into multiple independent random variables, without sacrificing any information about unknown parameters. A recent pap
Table of 99% credible intervals (CIs) for differences of b and d between strains with Topt ≤ 50 and Topt > 50. A 99% CI that includes zero indicates that there is a 99% probability that the two parame
For each gene, Chr/Mb denotes chromosome and genomic position (Megabases), dbSNP is the rs-identifier for the assayed SNP, and Nuc is the nucleotide substitution at a SNP. Frqassoc and Z-scores are wi