A Luminescent and Biocompatible PhotoCORM
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https://figshare.com/articles/dataset/A_Luminescent_and_Biocompatible_PhotoCORM/2471350
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资源简介：
The water-soluble rhenium(I) complex fac-[Re(bpy)(CO)3(thp)]+ (1) [CF3SO3– salt; bpy = 2,2′-bipyridine,
thp
= tris(hydroxymethyl)phosphine] is both strongly luminescent and photoactive
toward carbon monoxide release. It is stable in aerated aqueous media,
is incorporated into cells from the human prostatic carcinoma cell
line PPC-1, and shows no apparent cytotoxicity. Furthermore, the solvated
Re(I) photoproduct of CO release (2) is also luminescent,
a feature that allows one to track the transformation of 1 to 2 inside such cells using confocal fluorescence
microscopy. In this context, 1 is a very promising candidate
as a photoactivated CO releasing moiety (photoCORM) with potential
therapeutic applications.
创建时间：
2016-02-20
