Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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资源简介:
Mouse hair follicles undergo synchronized cycles. Cyclical regeneration and hair growth is fueled by hair follicle stem cells (HFSCs) and transit-amplifying cells (TACs). We used ChIP-seq to unfold genome-wide chromatin landscapes of H3K27ac and Med1 to identify super-enhancers and dissect their biological relevance in cell identity and plasticity of HFSCs in vivo and in vitro.
提供机构:
Regeneron Pharmaceuticals
创建时间:
2022-02-20



