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Mean values ± SEM of selected metabolic parameters in DIO-mice and lean, age-matched controls.

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†Area under blood glucose curves during a glucose tolerance test was calculated as described previously [52]. ††Whole-body insulin sensitivity indices during a glucose tolerance test was calculated as described in a previous study [43]. *, ** and *** indicate P<0.05, <0.001 and <0.0001, respectively, when the difference between DIO-mice and lean mice was analyzed (student t-test).

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2013-11-18
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