Data and code archive for project "Tracing caffeine and its metabolite in wastewater to understand the spread of SARS-CoV-2"

This dataset/code archive included all the data and R codes that were used to explore the universal and robust wastewater biomarkers for population normalization in the SARS-CoV-2 wastewater-based epidemiology. There are nine R code files to produce figures and tables.  The data included:

Raw data of weekly biomarkers (caffeine, paraxanthine, and PMMoV) wastewater concentrations, weekly new COVID-19 case numbers, SARS-CoV-2 N1/N2 copies in wastewater, wastewater flow rate 

A total of 2,624 wastewater samples (41 weeks) were collected weekly from May 2021- April 2022 from 64 wastewater treatment plants across Missouri, US;

pMMoV data was only available from Sep 13 2021-April 2022 for Missouri data;

Validation dataset from 10 wastewater treatment plants across Wisconsin, US, to test the relationship between wastewater biomarkers and population. 

Downloaded Apple mobility data during the pandemic 

Validation dataset for wastewater flowrate estimation using paraxanthine concentrations.