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CRISPR-Cas12a with an oncolytic adenovirus induces precise and cancer-specific genomic reprogramming of EGFR and efficient tumor regression

NIAID Data Ecosystem2026-03-11 收录

癌症基因治疗

CRISPRi基因编辑

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA560758 数据链接链接失效反馈

官方服务：

资源简介：

Targeted deep sequencing using human genome

应用场景：

创建时间：

2019-08-19

CRISPRi基因编辑

鲑鱼立克次氏体遗传操作

Piscirickettsia salmonis is the causative agent of Salmonid Rickettsial Septicemia (SRS), the main bacterial disease affecting the salmon industry in Chile. In this work, we implemented a Mobile-CRISP

NIAID Data Ecosystem60

The uncropped raw gel images.xlsx

CRISPRi基因编辑

凝胶电泳验证

Herein, we present the uncropped raw gel images associated with our manuscript titled " Enhancement of CRISPR-Cas12a System through Universal Circular RNA Design ," published in Cell Reports M

Figshare2025-04-29 更新40

File S2.zip

CRISPRi基因编辑

基因敲入序列分析

Annotated sequence files in .ape format (comparable with Genbank) of knock-ins generated by CRISPR/Cas9-mediated genome editing. Unmodified genomic sequence is also provided.

Figshare2023-03-14 更新20

CRISPR edited strains generated.

CRISPRi基因编辑

微生物菌株开发

S6 Table lists information regarding alleles, strain names and reagents that were generated and used, respectively, during this study for CRISPR/Cas9 mediated genome engineering. (XLSX)

Figshare2021-07-01 更新50

AlleleAnalyzer supporting data

CRISPRi基因编辑

sgRNA优化

The CRISPR/Cas system is a highly specific genome editing tool capable of distinguishing alleles differing by even a single base pair. Target sites might carry genetic variations that are not distin

DataCite Commons2026-03-11 更新20

CRISPR-Cas12a with an oncolytic adenovirus induces precise and cancer-specific genomic reprogramming of EGFR and efficient tumor regression

资源简介：

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