Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ446 (compound 4f)

NIAID Data Ecosystem2026-05-01 收录

HIV整合酶抑制剂

抗病毒药物结构生物学

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Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ446 (compound 4f)

创建时间：

2024-03-20

5-(4-FLUOROPHENYL)-3-HYDROXY-6-[4-(1H-1,2,3,4-TETRAZOL-5-YL)PHENYL]-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 pH1N1 endonuclease

流感病毒内切酶抑制剂

抗病毒药物结构生物学

5-(4-FLUOROPHENYL)-3-HYDROXY-6-[4-(1H-1,2,3,4-TETRAZOL-5-YL)PHENYL]-1,2-DIHYDROPYRIDIN-2-ONE bound to influenza 2009 pH1N1 endonuclease Descriptor: 5-(4-fluorophenyl)-3-hydroxy-6-[4-(1H-tetrazol-5-yl)

Protein Data Bank Japan2024-02-28 更新70

PFV intasome with inhibitor XZ-259

HIV整合酶抑制剂

病毒结构生物学

PFV intasome with inhibitor XZ-259 Descriptor: 17 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (TRANSFERRED STRAND) *AP*CP*A)-3', 19 NUCLEOTIDE PREPROCESSED PFV DONOR DNA (NON-TRANSFERRED STRAND), 2-(3-chlor

Protein Data Bank Japan2023-12-20 更新40

Crystal structure of HIV-1 integrase catalytic core domain in complex with 2-(tert-butoxy)-2-[3-(3,4-dihydro-2H-1-benzopyran-6-yl)-6-methanesulfonamido-2,3',4',5-tetramethyl-[1,1'-biphenyl]-4-yl]acetic acid

HIV整合酶抑制剂

抗病毒药物结构生物学

NIAID Data Ecosystem20

Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1

HIV整合酶抑制剂

抗病毒药物机制

Dissociation of biochemical and antiretroviral activities of Integrase-LEDGF Allosteric Inhibitors revealed by resistance of A125 polymorphic HIV-1 Descriptor: (2~{S})-2-[4-(4,4-dimethylcyclohexen-1-y

Protein Data Bank Japan2024-11-13 更新50

HIV Integrase core domain in complex with inhibitor 2-(5-methyl-2-(2-(thiophen-2-yl)ethynyl)-1-benzofuran-3-yl)acetic acid

HIV整合酶抑制剂

结构生物学

HIV Integrase core domain in complex with inhibitor 2-(5-methyl-2-(2-(thiophen-2-yl)ethynyl)-1-benzofuran-3-yl)acetic acid Descriptor: 2-[5-methyl-2-(2-thiophen-2-ylethynyl)-1-benzofuran-3-yl]ethanoic

Protein Data Bank Japan2024-10-30 更新40

Structure of HIV cleaved synaptic complex (CSC) intasome bound with magnesium and INSTI XZ446 (compound 4f)

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