Structure of BACE bound to SCH12472
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Structure of BACE bound to SCH12472 Descriptor: 3-[2-(3-chlorophenyl)ethyl]pyridin-2-amine, Beta-secretase 1 Authors: Strickland, C, Wang, Y. Deposit date: 2009-11-11 Release date: 2010-01-19 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Application of Fragment-Based NMR Screening, X-ray Crystallography, Structure-Based Design, and Focused Chemical Library Design to Identify Novel muM Leads for the Development of nM BACE-1 (beta-Site APP Cleaving Enzyme 1) Inhibitors. J.Med.Chem., 53, 2010
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2009-11-11
