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Homo sapiens Transcriptome or Gene expression. Homo sapiens

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1018971
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mTORC2-deficient human embryonic stem cell (hESC) lines have been generated by disrupting RICTOR gene that encodes the specific subunit of mTORC2. Although RICTOR-knockout (RIC-KO) hESCs can maintain self-renewal and the expression of pluripotent markers, RIC-KO considerably impairs cell adhesion and cell-cell interaction in hESCs by disturbing RhoA/Rac signaling pathways. The difference of transcriptomic profiles between WT and RIC-KO hESCs needs to be further explored.
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2023-09-19
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