Whole cell proteome of OCI-AML3 FKBP12(F36V) cells with dTAG-13 treatment
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https://www.omicsdi.org/dataset/pride/PXD045357
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资源简介：
The nucleolar scaffold protein NPM1 acts as a multifunctional regulator of cellular homeostasis, genome integrity, and stress response. NPM1 mutations, known as NPM1c variants that promote its aberrant cytoplasmic localization, are the most frequent genetic alterations in acute myeloid leukemia (AML). A hallmark of AML cells is their dependency on elevated autophagic flux. In order to identify the proteome changes upon NPM1 and NPM1c overexpression, we performed TMT-labeled mass spectrometry analysis of whole cell lysates.
创建时间：
2023-10-28
