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G9a-dependent gene expression in mouse AML cells

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NIAID Data Ecosystem2026-03-11 收录
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The methyltransferase G9a was found to play a role in the disease progression of a murine model of AML. Mouse HSPCs were transformed with HoxA9/Meis1 and treated with G9a/GLP inhibitor UNC0638. We used microarrays to detail the global program of gene expression that depends on the methyltransferase activity of G9a in murine AML cells.

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2019-03-04
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