Single-cell RNA-sequencing of murine atrioventricular node macrophages

Tissue-resident macrophages abound in the distal atrioventricular (AV) node of the heart, electrically couple to conducting cardiomyocytes via Connexin (Cx) 43-containing gap junctions and are implicated in normal and aberrant cardiac conduction. Comparison of 76 single-cell transcriptomes from murine AV node macrophages.心脏远端房室结（atrioventricular node，AV node）中富含组织驻留巨噬细胞（Tissue-resident macrophages），此类细胞通过携带连接蛋白（Connexin，Cx）43的缝隙连接与传导性心肌细胞实现电偶联，并参与正常及异常的心脏传导过程。本数据集针对76份小鼠房室结巨噬细胞的单细胞转录组（single-cell transcriptomes）展开了比对分析。