Crystal structure of phosphatidyl serine synthase (PSS) in transition state.

Crystal structure of phosphatidyl serine synthase (PSS) in transition state. Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2-amino-3-[[[(2R,3S,4R,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-[(2R)-2,3-bis[[(Z)-octadec-9-enoyl]oxy]propoxy]-dihydroxy-lambda^5-phosphanyl]oxy-propanoic acid, 5'-O-[(R)-{[(S)-{(2R)-2,3-bis[(9E)-octadec-9-enoyloxy]propoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, ... Authors: Yildiz, O, Centola, M. Deposit date: 2021-09-10 Release date: 2021-12-08 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Crystal structures of phosphatidyl serine synthase PSS reveal the catalytic mechanism of CDP-DAG alcohol O-phosphatidyl transferases Nat Commun, 12, 2021