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ERBB2/HER2 transmembrane and juxtamembrane domain mutations in cancer

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NIAID Data Ecosystem2026-03-10 收录
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In this study, we identified several recurrent activating HER2 somatic mutations in transmembrane and juxtamembrane domain in multiple cancers and demonstrate that patients carryingthese mutations are candidates for anti-HER2 therapy. We have also identified a germline mutation in HER2 transmembrane domain.EGA study EGAS00001003213

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2018-10-31
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