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Mitochondrial Fission 1 (FIS1) knockdown effect on the transcriptome of leukemia cell line MOLM-13 cells

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE114111
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To explore the function of Mitochondrial Fission 1 (FIS1) in acute myeloid leukemia (AML), we used shRNA to knock down the expression of FIS1 in leukemia cell line MOLM-13 cells and performed RNA-seq experiments to profile transcriptional changes upon FIS1 depletion. Expression of FIS1 is knocked down using two indepedent shRNA sequences in leukemia cell line MOLM-13 cells. Technical triplicates are performed. Total RNA is isolated and subjected to RNA-seq analysis.
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2019-03-27
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